MPOHOKI88 GenoCAD uses grammars, which are either opensource or user generated "rules" which include the available genes and known gene interactions for cloning organisms. Clotho framework uses the Biobrick standard rules. Kobayashi H, Kaern M, Araki M, Chung K, Gardner TS, Cantor CR, Collins JJ (June 2004). "Programmable cells: interfacing natural and engineered gene networks".|Anda dapat Membantu Wikipedia dengan Mengembangkannya